diff --git a/packages/vant/src/picker/Picker.tsx b/packages/vant/src/picker/Picker.tsx
index fbc28fa3d..a0e606114 100644
--- a/packages/vant/src/picker/Picker.tsx
+++ b/packages/vant/src/picker/Picker.tsx
@@ -9,7 +9,6 @@ import {
 
 // Utils
 import {
-  isDef,
   extend,
   unitToPx,
   truthProp,
@@ -21,6 +20,12 @@ import {
   HAPTICS_FEEDBACK,
   BORDER_UNSET_TOP_BOTTOM,
 } from '../utils';
+import {
+  getColumnsType,
+  findOptionByValue,
+  formatCascadeColumns,
+  getFirstEnabledOption,
+} from './utils';
 
 // Composables
 import { useChildren } from '@vant/use';
@@ -34,7 +39,6 @@ import Column, { PICKER_KEY } from './PickerColumn';
 import type {
   PickerColumn,
   PickerExpose,
-  PickerOption,
   PickerFieldNames,
   PickerToolbarPosition,
 } from './types';
@@ -76,77 +80,41 @@ export default defineComponent({
     const selectedValues = ref(props.modelValue);
     const currentColumns = ref<PickerColumn[]>([]);
 
-    const {
-      text: textKey,
-      value: valueKey,
-      children: childrenKey,
-    } = extend(
-      {
-        text: 'text',
-        value: 'value',
-        children: 'children',
-      },
-      props.columnsFieldNames
-    );
-
     const { children, linkChildren } = useChildren(PICKER_KEY);
 
     linkChildren();
 
+    const fields = computed(
+      (): Required<PickerFieldNames> =>
+        extend(
+          {
+            text: 'text',
+            value: 'value',
+            children: 'children',
+          },
+          props.columnsFieldNames
+        )
+    );
     const optionHeight = computed(() => unitToPx(props.optionHeight));
-
-    const dataType = computed(() => {
-      const firstColumn = props.columns[0];
-      if (Array.isArray(firstColumn)) {
-        return 'multiple';
-      }
-      if (childrenKey in firstColumn) {
-        return 'cascade';
-      }
-      return 'default';
-    });
-
-    const findOption = (options: PickerOption[], value: number | string) =>
-      options.find((option) => option[valueKey] === value);
-
-    const formatCascade = () => {
-      const formatted: PickerColumn[] = [];
-
-      let cursor: PickerOption | undefined = {
-        [childrenKey]: props.columns,
-      };
-      let columnIndex = 0;
-
-      while (cursor && cursor[childrenKey]) {
-        const options: PickerOption[] = cursor[childrenKey];
-        const value = selectedValues.value[columnIndex];
-
-        cursor = isDef(value) ? findOption(options, value) : undefined;
-
-        if (!cursor && options.length) {
-          const firstValue = options[0][valueKey];
-          selectedValues.value[columnIndex] = firstValue;
-          cursor = findOption(options, firstValue);
-        }
-
-        columnIndex++;
-        formatted.push(options);
-      }
-
-      return formatted;
-    };
+    const columnsType = computed(() =>
+      getColumnsType(props.columns, fields.value)
+    );
 
     const selectedOptions = computed(() =>
       currentColumns.value.map((options, index) =>
-        findOption(options, selectedValues.value[index])
+        findOptionByValue(options, selectedValues.value[index], fields.value)
       )
     );
 
     const onChange = (value: number | string, columnIndex: number) => {
       selectedValues.value[columnIndex] = value;
 
-      if (dataType.value === 'cascade') {
-        currentColumns.value = formatCascade();
+      if (columnsType.value === 'cascade') {
+        currentColumns.value = formatCascadeColumns(
+          props.columns,
+          fields.value,
+          selectedValues
+        );
       }
 
       emit('change', {
@@ -222,10 +190,9 @@ export default defineComponent({
         <Column
           v-slots={{ option: slots.option }}
           value={selectedValues.value[columnIndex]}
-          textKey={textKey}
+          fields={fields.value}
           options={options}
           readonly={props.readonly}
-          valueKey={valueKey}
           allowHtml={props.allowHtml}
           optionHeight={optionHeight.value}
           swipeDuration={props.swipeDuration}
@@ -265,26 +232,27 @@ export default defineComponent({
       );
     };
 
+    const formatColumns = (
+      columns: PickerColumn | PickerColumn[]
+    ): PickerColumn[] => {
+      switch (columnsType.value) {
+        case 'multiple':
+          return columns as PickerColumn[];
+        case 'cascade':
+          return formatCascadeColumns(columns, fields.value, selectedValues);
+        default:
+          return [columns];
+      }
+    };
+
     watch(
       () => props.columns,
-      () => {
-        const { columns } = props;
-
-        switch (dataType.value) {
-          case 'multiple':
-            currentColumns.value = columns;
-            break;
-          case 'cascade':
-            currentColumns.value = formatCascade();
-            break;
-          default:
-            currentColumns.value = [columns];
-            break;
-        }
-
+      (columns) => {
+        currentColumns.value = formatColumns(columns);
         currentColumns.value.forEach((options, index) => {
           if (selectedValues.value[index] === undefined && options.length) {
-            selectedValues.value[index] = options[0][valueKey];
+            selectedValues.value[index] =
+              getFirstEnabledOption(options)[fields.value.value];
           }
         });
 
diff --git a/packages/vant/src/picker/PickerColumn.tsx b/packages/vant/src/picker/PickerColumn.tsx
index a9285bbd6..ceafb27f0 100644
--- a/packages/vant/src/picker/PickerColumn.tsx
+++ b/packages/vant/src/picker/PickerColumn.tsx
@@ -1,4 +1,10 @@
-import { ref, watch, defineComponent, type InjectionKey } from 'vue';
+import {
+  ref,
+  watchEffect,
+  defineComponent,
+  type PropType,
+  type InjectionKey,
+} from 'vue';
 
 // Utils
 import {
@@ -9,6 +15,7 @@ import {
   createNamespace,
   makeRequiredProp,
 } from '../utils';
+import { getElementTranslateY, findIndexOfEnabledOption } from './utils';
 
 // Composables
 import { useParent } from '@vant/use';
@@ -16,7 +23,11 @@ import { useTouch } from '../composables/use-touch';
 import { useExpose } from '../composables/use-expose';
 
 // Types
-import type { PickerOption, PickerColumnProvide } from './types';
+import type {
+  PickerOption,
+  PickerFieldNames,
+  PickerColumnProvide,
+} from './types';
 
 const DEFAULT_DURATION = 200;
 
@@ -28,12 +39,6 @@ const MOMENTUM_DISTANCE = 15;
 
 const [name, bem] = createNamespace('picker-column');
 
-function getElementTranslateY(element: Element) {
-  const { transform } = window.getComputedStyle(element);
-  const translateY = transform.slice(7, transform.length - 1).split(', ')[5];
-  return Number(translateY);
-}
-
 export const PICKER_KEY: InjectionKey<PickerColumnProvide> = Symbol(name);
 
 export default defineComponent({
@@ -41,10 +46,9 @@ export default defineComponent({
 
   props: {
     value: numericProp,
-    textKey: makeRequiredProp(String),
+    fields: makeRequiredProp(Object as PropType<Required<PickerFieldNames>>),
     options: makeArrayProp<PickerOption>(),
     readonly: Boolean,
-    valueKey: makeRequiredProp(String),
     allowHtml: Boolean,
     optionHeight: makeRequiredProp(Number),
     swipeDuration: makeRequiredProp(numericProp),
@@ -70,24 +74,12 @@ export default defineComponent({
     const baseOffset = () =>
       (props.optionHeight * (+props.visibleOptionNum - 1)) / 2;
 
-    const adjustIndex = (index: number) => {
-      index = clamp(index, 0, count());
-
-      for (let i = index; i < count(); i++) {
-        if (!props.options[i].disabled) return i;
-      }
-      for (let i = index - 1; i >= 0; i--) {
-        if (!props.options[i].disabled) return i;
-      }
-      return 0;
-    };
-
     const updateValueByIndex = (index: number) => {
-      index = adjustIndex(index);
+      const enabledIndex = findIndexOfEnabledOption(props.options, index);
+      const offset = -enabledIndex * props.optionHeight;
 
-      const offset = -index * props.optionHeight;
       const trigger = () => {
-        const { value } = props.options[index];
+        const value = props.options[enabledIndex][props.fields.value];
         if (value !== props.value) {
           emit('change', value);
         }
@@ -214,9 +206,9 @@ export default defineComponent({
       };
 
       return props.options.map((option, index) => {
-        const text = option[props.textKey];
+        const text = option[props.fields.text];
         const { disabled } = option;
-        const value: string | number = option[props.valueKey];
+        const value: string | number = option[props.fields.value];
         const data = {
           role: 'button',
           style: optionStyle,
@@ -244,16 +236,14 @@ export default defineComponent({
     useParent(PICKER_KEY);
     useExpose({ stopMomentum });
 
-    watch(
-      () => props.value,
-      (value) => {
-        const index = props.options.findIndex(
-          (option) => option[props.valueKey] === value
-        );
-        const offset = -adjustIndex(index) * props.optionHeight;
-        currentOffset.value = offset;
-      }
-    );
+    watchEffect(() => {
+      const index = props.options.findIndex(
+        (option) => option[props.fields.value] === props.value
+      );
+      const enabledIndex = findIndexOfEnabledOption(props.options, index);
+      const offset = -enabledIndex * props.optionHeight;
+      currentOffset.value = offset;
+    });
 
     return () => (
       <div
diff --git a/packages/vant/src/picker/demo/data.ts b/packages/vant/src/picker/demo/data.ts
index 1b2a57dc6..24caf3de9 100644
--- a/packages/vant/src/picker/demo/data.ts
+++ b/packages/vant/src/picker/demo/data.ts
@@ -144,7 +144,7 @@ export const cascadeColumns = {
   ],
 };
 
-export const cascadeColumnsCustomKey = {
+export const customKeyColumns = {
   'zh-CN': [
     {
       cityName: '浙江',
@@ -202,3 +202,16 @@ export const cascadeColumnsCustomKey = {
     },
   ],
 };
+
+export const disabledColumns = {
+  'zh-CN': [
+    { text: '杭州', value: 'Hangzhou', disabled: true },
+    { text: '宁波', value: 'Ningbo' },
+    { text: '温州', value: 'Wenzhou' },
+  ],
+  'en-US': [
+    { text: 'Delaware', value: 'Delaware', disabled: true },
+    { text: 'Florida', value: 'Florida' },
+    { text: 'Georqia', value: 'Georqia' },
+  ],
+};
diff --git a/packages/vant/src/picker/index.ts b/packages/vant/src/picker/index.ts
index 4b9739a56..bae468b68 100644
--- a/packages/vant/src/picker/index.ts
+++ b/packages/vant/src/picker/index.ts
@@ -10,7 +10,9 @@ export type {
   PickerInstance,
   PickerFieldNames,
   PickerToolbarPosition,
+  PickerCancelEventParams,
   PickerChangeEventParams,
+  PickerConfirmEventParams,
 } from './types';
 
 declare module 'vue' {
diff --git a/packages/vant/src/picker/utils.ts b/packages/vant/src/picker/utils.ts
new file mode 100644
index 000000000..4702c2bb7
--- /dev/null
+++ b/packages/vant/src/picker/utils.ts
@@ -0,0 +1,88 @@
+import { isDef, clamp } from '../utils';
+import type { Ref } from 'vue';
+import type { PickerOption, PickerColumn, PickerFieldNames } from './types';
+
+export function getFirstEnabledOption(options: PickerOption[]) {
+  return options.find((option) => !option.disabled) || options[0];
+}
+
+export function getColumnsType(
+  columns: PickerColumn | PickerColumn[],
+  fields: Required<PickerFieldNames>
+) {
+  const firstColumn = columns[0];
+  if (firstColumn) {
+    if (Array.isArray(firstColumn)) {
+      return 'multiple';
+    }
+    if (fields.children in firstColumn) {
+      return 'cascade';
+    }
+  }
+  return 'default';
+}
+
+export function findIndexOfEnabledOption(
+  options: PickerOption[],
+  index: number
+) {
+  index = clamp(index, 0, options.length);
+
+  for (let i = index; i < options.length; i++) {
+    if (!options[i].disabled) return i;
+  }
+  for (let i = index - 1; i >= 0; i--) {
+    if (!options[i].disabled) return i;
+  }
+
+  return 0;
+}
+
+export function findOptionByValue(
+  options: PickerOption[],
+  value: number | string,
+  fields: Required<PickerFieldNames>
+) {
+  const index = options.findIndex((option) => option[fields.value] === value);
+  const enabledIndex = findIndexOfEnabledOption(options, index);
+  return options[enabledIndex];
+}
+
+export function formatCascadeColumns(
+  columns: PickerColumn | PickerColumn[],
+  fields: Required<PickerFieldNames>,
+  selectedValues: Ref<Array<number | string>>
+) {
+  const formatted: PickerColumn[] = [];
+
+  let cursor: PickerOption | undefined = {
+    [fields.children]: columns,
+  };
+  let columnIndex = 0;
+
+  while (cursor && cursor[fields.children]) {
+    const options: PickerOption[] = cursor[fields.children];
+    const value = selectedValues.value[columnIndex];
+
+    cursor = isDef(value)
+      ? findOptionByValue(options, value, fields)
+      : undefined;
+
+    if (!cursor && options.length) {
+      const firstValue = getFirstEnabledOption(options)[fields.value];
+      selectedValues.value[columnIndex] = firstValue;
+      cursor = findOptionByValue(options, firstValue, fields);
+    }
+
+    columnIndex++;
+    formatted.push(options);
+  }
+
+  return formatted;
+}
+
+export function getElementTranslateY(element: Element) {
+  const { transform } = window.getComputedStyle(element);
+  const translateY = transform.slice(7, transform.length - 1).split(', ')[5];
+  return Number(translateY);
+}